« Back
Home /
Glutaminyl cyclases-IN-1

Glutaminyl cyclases-IN-1

Item no.	HY-151132-100mg
Manufacturer	MedChem Express
Amount	100 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Citations	[1]Eunsun Park, et al. 2-Amino-1,3,4-thiadiazoles as Glutaminyl Cyclases Inhibitors Increase Phagocytosis through Modification of CD47-SIRPα Checkpoint. ACS Med. Chem. Lett. 2022.
Smiles	COC1=C(C=CC(CN2C=NC3=CC(C4=NN=C(S4)N)=CC=C32)=C1)OCCCN5CCCCC5
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	IsoQC-IN-1
Available
Product Description	Glutaminyl cyclases-IN-1 (IsoQC-IN-1) is a potent glutaminyl cyclases (QC) inhibitor with IC50 values of 12 nM and 73 nM for human QC and isoQC, respectively. Glutaminyl cyclases-IN-1 can selectively interfere with the interaction of CD47/SIRPα through isoQC inhibition, and enhances the increased phagocytic activity of both THP-1 and U937 macrophages[1].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	478.61
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	10 mM in DMSO
Manufacturers Target	Others
Pathway	Others
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 mg

available

Request delivery time