MS159

Item no.	HY-151101-100mg
Manufacturer	MedChem Express
CASRN	3031353-59-7
Amount	100 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	98.28
Formula	C43H40N8O10
Citations	[1]Fanye Meng, et al. Discovery of a First-in-Class Degrader for Nuclear Receptor Binding SET Domain Protein 2 (NSD2) and Ikaros/Aiolos. J Med Chem. 2022 Aug 11;65(15):10611-10625.
Smiles	O=C(NCCCOC1=CN=C(C=C1)NC(C2=CC=C(C=C2)CN(C3CC3)C(C4=CC=C5NC(COC5=C4)=O)=O)=O)CNC6=CC=CC7=C6C(N(C7=O)C8CCC(NC8=O)=O)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	MS159 is a potent nuclear receptor binding SET structural domain protein 2 (NSD2) PROTACdegrader. MS159 inhibits the growth of tumour cells. MS159 is a useful chemical tool for exploring the role of NSD2 in health and disease[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	828.83
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic; heat to 60°C)
Target	PROTACs
Manufacturers Target	PROTACs
Manufacturers Pathway	PROTAC
Manufacturers Product type	Reference compound

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