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DNA Gyrase-IN-2

DNA Gyrase-IN-2

Item no.	HY-147818-100mg
Manufacturer	MedChem Express
CASRN	2522666-80-2
Amount	100 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Citations	[1]Mohamed A Omar, et al. Novel anti-tubercular and antibacterial based benzosuberone-thiazole moieties: Synthesis, molecular docking analysis, DNA gyrase supercoiling and ATPase activity. Bioorg Chem. 2020 Nov;104:104316.
Smiles	O=C1N=C(N/N=C2N=C(N/N=C3CCCCC4=CC=CC=C4/3)SC\2)S/C1=N\NC5=CC=C(C)C=C5
ECLASS 5.1	32160000
ECLASS 6.1	32160000
ECLASS 8.0	32160000
ECLASS 9.0	32160000
ECLASS 10.0.1	32160000
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	DNA Gyrase-IN-2 (Compound 22a) is a bacterial DNA gyrase B inhibitor with IC50s of 3.29-10.49 and 4.41-5.61 µM for E. coli DNA gyrase and M. tuberculosis DNA gyrase. Anti-tubercular and antibacterial activity[1].
Shipping	Room temperature
Manufacturers Applications	COVID-19-anti-virus
MolecularWeight	504.63
Clinical_Information	No Development Reported
Manufacturers Research_Area	Infection
Solubility	10 mM in DMSO
Manufacturers Target	Bacterial; DNA/RNA Synthesis
Pathway	Anti-infection; Cell Cycle/DNA Damage
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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