Comparison

PROTAC IRAK3 degrade-1 (formic) European Partner

Item no. HY-142662A-5mg
Manufacturer MedChem Express
Amount 5 mg
Category
Type Reagents
Specific against other
Purity 98.10
Formula C48H65N11O8
Citations [1]Degorce SL, et al. Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase. J Med Chem. 2020 Sep 24;63(18):10460-10473.
Smiles O=C1C2=CC(N3CCN(CC3)CCC4CCN(CC4)C(CCC(N5CCN([C@@]6([H])CC[C@H](CC6)NC7=NC=NN8C7=C(C(C)C)C=C8)CC5)=O)=O)=CC=C2C(N1C9C(NC(CC9)=O)=O)=O.O=CO
ECLASS 10.1 42051003
ECLASS 11.0 42051003
UNSPSC 12000000
Available
Product Description
PROTAC IRAK3 degrade-1 (compound 23) formic is a potent and selective degrader of IRAK3 (IC50=5 nM)[1].
StorageTemperature
4°C (Powder, sealed storage, away from moisture and light)
Shipping
Room Temperature
Manufacturers Applications
Cancer-programmed cell death
MolecularWeight
924.10
Clinical_Information
No Development Reported
Manufacturers Research_Area
Others
Solubility
DMSO : 150 mg/mL (ultrasonic)
Manufacturers Target
PROTACs
Pathway
PROTAC
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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