Comparison

DOTA-PEG5-C6-DBCO European Partner

Item no. HY-140314-10mg
Manufacturer MedChem Express
Amount 10 mg
Category
Type Reagents
Specific against other
Purity 96.40
Formula C49H71N7O14
Citations [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Smiles O=C(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)CCCCC(NCCOCCOCCOCCOCCOCCNC(CN4CCN(CCN(CCN(CC4)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O
ECLASS 5.1 32160401
ECLASS 6.1 32160401
ECLASS 8.0 42051003
ECLASS 9.0 42051003
ECLASS 10.0.1 42051003
ECLASS 10.1 42051003
ECLASS 11.0 42051003
UNSPSC 12000000
Available
Product Description
DOTA-PEG5-C6-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DOTA-PEG5-C6-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
StorageTemperature
-20°C, 3 years (Powder)
Shipping
Blue Ice
Manufacturers Applications
Cancer-programmed cell death
MolecularWeight
982.13
Clinical_Information
No Development Reported
Manufacturers Research_Area
Cancer
Solubility
DMSO : 125 mg/mL (ultrasonic)|H2O : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target
PROTAC Linkers
Isoform
PEG Linkers
Pathway
PROTAC
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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