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Thalidomide-4-O-C6-NH2 (hydrochloride)

Thalidomide-4-O-C6-NH2 (hydrochloride)

Item no.	HY-135250B-10mg
Manufacturer	MedChem Express
CASRN	2245697-88-3
Amount	10 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	98.87
Formula	C19H24ClN3O5
Citations	[1]Erb MA, et al. Transcription control by the ENL YEATS domain in acute leukaemia. Nature. 2017 Mar 9;543(7644):270-274.
Smiles	O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCCCCCN)=O.[H]Cl
ECLASS 5.1	32169090
ECLASS 6.1	32169090
ECLASS 8.0	32169090
ECLASS 9.0	32169090
ECLASS 10.0.1	32169090
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	2245697-88-3
Available
Product Description	Thalidomide-4-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	409.86
Clinical_Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 83.33 mg/mL (ultrasonic)\|H2O : 25 mg/mL (ultrasonic)
Manufacturers Target	Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Isoform	Cereblon
Pathway	Apoptosis; Autophagy; PROTAC

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