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1-Palmitoyl-sn-glycero-3-phosphocholine

1-Palmitoyl-sn-glycero-3-phosphocholine

Item no.	HY-125783-100mg
Manufacturer	MedChem Express
CASRN	17364-16-8
Amount	100 mg
Quantity options	100 mg 1 ea 25 mg 50 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.90
Formula	C24H50NO7P
Citations	[1]Choi S, et al. Superoxide generated by lysophosphatidylcholine induces endothelial nitric oxide synthase downregulation in human endothelial cells. Cell Physiol Biochem. 2010;25(2-3):233-40.<br/>[2]Qin X, et al. Lysophosphatidylcholine perpetuates macrophage polarization toward classically activated phenotype in inflammation. Cell Immunol. 2014 May-Jun;289(1-2):185-90.<br/>[3]Hasegawa H, et al. Lysophosphatidylcholine enhances the suppressive function of human naturally occurring regulatory T cells through TGF-β production. Biochem Biophys Res Commun. 2011 Nov 25;415(3):526-31.<br/>[4]Yan JJ, et al. Therapeutic effects of lysophosphatidylcholine in experimental sepsis. Nat Med. 2004 Feb;10(2):161-7.
Smiles	CCCCCCCCCCCCCCCC(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	1-Palmitoyl-sn-glycero-3-phosphocholine is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis[1][2][3][4].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
MolecularWeight	495.63
Clinical Information	No Development Reported
Manufacturers Research Area	Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Solubility	H2O : 50 mg/mL (ultrasonic)
Target	Endogenous Metabolite
Manufacturers Target	Endogenous Metabolite
Isoform	Human Endogenous Metabolite
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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