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Carotegrast methyl

Carotegrast methyl

Item no.	HY-124290-25mg
Manufacturer	MedChem Express
CASRN	401905-67-7
Amount	25 mg
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	98.89
Formula	C28H26Cl2N4O5
Citations	[1]Toshihiko Sugiura, et al. Oral treatment with a novel small molecule alpha 4 integrin antagonist, AJM300, prevents the development of experimental colitis in mice. J Crohns Colitis. 2013 Dec;7(11):e533-42.
Smiles	O=C([C@@H](NC(C1=C(C=CC=C1Cl)Cl)=O)CC2=CC=C(C=C2)N3C(N(C4=C(C3=O)C=C(C=C4)N(C)C)C)=O)OC
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	AJM300
Available
Product Description	Carotegrast methyl (AJM300) is an orally active and selective α4 integrin antagonist. HCA2969, an active metabolite of Carotegrast methyl, is a specific and dual α4β1/α4β7 integrin antagonist. Carotegrast methyl prevents the development of colitis in mice[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	569.44
Clinical Information	Launched
Manufacturers Research Area	Inflammation/Immunology
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Integrin
Manufacturers Target	Integrin
Manufacturers Pathway	Cytoskeleton
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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