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QAQ (dichloride)

QAQ (dichloride)

Item no.	HY-110358-10mg
Manufacturer	MedChem Express
Amount	10 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Other Chemicals
Type	Reagents
Specific against	other
Purity	99.30
Formula	C28H44Cl2N6O2
Citations	[1]Timm Fehrentz, et al. Exploring the Pharmacology and Action Spectra of Photochromic Open-Channel Blockers. Chembiochem. 2012 Aug 13;13(12):1746-9.<br/>[2]Alexandre Mourot, et al.Photochromic Potassium Channel Blockers: Design and Electrophysiological Characterization. Methods Mol Biol. 2013;995:89-105.
Smiles	O=C(NC1=CC=C(/N=N/C2=CC=C(NC(C[N+](CC)(CC)CC)=O)C=C2)C=C1)C[N+](CC)(CC)CC.[Cl-].[Cl-]
ECLASS 10.1	42051003
ECLASS 11.0	42051003
UNSPSC	12000000
Available
Product Description	QAQ dichloride, a photoswitchable voltage-gated Nav and Kv channels blocker, blocks channels in its trans form (of the azobenzene photoswitch), but not in its cis form. QAQ dichloride is membrane-impermeant and only infiltrates pain-sensing neurons that express endogenous import channels. QAQ dichloride acts as a light-sensitive analgesic and can be used for studying of signaling mechanisms in acute and chronic pain[1][2].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	567.59
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology
Solubility	DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Sodium Channel
Manufacturers Target	Sodium Channel
Manufacturers Pathway	Membrane Transporter/Ion Channel
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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