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Abeprazan (hydrochloride)

Abeprazan (hydrochloride)

Item no.	HY-109079A-10mg
Manufacturer	MedChem Express
CASRN	1902954-87-3
Amount	10 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.84
Formula	C19H18ClF3N2O3S
Citations	[1]Sunwoo J, et al. Safety, tolerability, pharmacodynamics and pharmacokinetics of DWP14012, a novel potassium-competitive acid blocker, in healthy male subjects. Aliment Pharmacol Ther. 2018 Jul;48(2):206-218.
Smiles	CNCC1=CN(S(=O)(C2=CC=CC(F)=C2)=O)C(C3=CC=C(F)C=C3F)=C1OC.[H]Cl
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	DWP14012 (hydrochloride); Fexuprazan (hydrochloride)
Available
Product Description	Abeprazan hydrochloride (DWP14012 hydrochloride) is a potassium-competitive acid blocker. Abeprazan hydrochloride inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan hydrochloride is developed as a potential alternative to proton pump inhibitor for the treatment of acid-related diseases[1].
StorageTemperature	-20°C (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
MolecularWeight	446.87
Clinical Information	Phase 4
Manufacturers Research Area	Metabolic Disease
Solubility	DMSO : 25 mg/mL (ultrasonic)
Target	Proton Pump
Manufacturers Target	Proton Pump
Manufacturers Pathway	Membrane Transporter/Ion Channel
Manufacturers Product type	Reference compound

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