AP521

Item no.	HY-100166-100mg
Manufacturer	MedChem Express
CASRN	151227-08-6
Amount	100 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	98.96
Formula	C20H19ClN2O3S
Citations	[1]Kasahara K, et al. The effects of AP521, a novel anxiolytic drug, in three anxiety models and on serotonergic neural transmission in rats. J Pharmacol Sci. 2015 Jan;127(1):109-16.
Smiles	O=C([C@H]1CC(C2=CC=CC=C2S3)=C3CN1)NCC4=CC=C(OCO5)C5=C4.[H]Cl
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	AP521 is an agonist of human 5-HT1A receptor with an IC50 of 94 nM.
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	402.89
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : 25 mg/mL (ultrasonic)
Target	5-HT Receptor
Manufacturers Target	5-HT Receptor
Isoform	5-HT1 Receptor; 5-HT5 Receptor; 5-HT7 Receptor
Manufacturers Pathway	GPCR/G Protein; Neuronal Signaling
Manufacturers Product type	Reference compound

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