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PF-05221304(Clesacostat)

PF-05221304(Clesacostat)

Item no.	DCC-DC44535-250mg
Manufacturer	DCChemicals
CASRN	1370448-25-1
Amount	250 mg
Category	Reagents & Chemicals Molecules
Type	Chemicals
Applications	IC, IS
Specific against	other
Smiles	O=C(O)C1=CC=C(C2=NC(OC)=CC(C(N3CCC(C4)(CC3)CC5=C(N(C(C)C)N=C5)C4=O)=O)=C2)C=C1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Fields of application	PF-05221304 is an orally bioavailable, liver-directed and dual ACC1 (and ACC2) inhibitor with IC50s of 7.5 nM for rat ACC1, 8.2 nM for rat ACC2, 12.4 nM for human ACC1 and 8.7 nM for human ACC2. PF-05221304 is a substrate for organic anion transport polypeptides. PF-05221304 directly improves a variety of non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH) pathogenic factors.
MOLECULE WEIGHT	502, 56

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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Delivery expected until 10/11/2024

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