Product info |
Dextran Size: 70 kDaFluorescent Dye Label: AFDye 488Volume (@ 5 mg/mL Fe): 0.5 mLGeneral InformationFluorescent, Biotin functionalized Dextran coated crosslinked iron oxide nanoparticles (CLIO-BIOTD) have 1-3 superparamagnetic Fe3O4 iron oxide cores (8-10 nm in diameter) imbedded within the matrix of dextran strands of 40 or 70 kDa in size. Dextran strands are crosslinked to prevent their disassociation, ensuring long-term stability. Biotin and fluorescence dye are covalently conjugated to the nanoparticle surface.Features:SuperparamagneticFluorescently labeled (AFDye 488, AFDye 555, AFDye 647, or IR750 dye)Highly biocompatible, non-toxicLong term stable under physiological conditions40 kDa and 70 kDa dextran coats are availableEasy loading of biomolecules such as Antibodies through Streptavidin-Biotin interaction Applications:In vitro and in vivo dual magnetic and fluorescence labels for cells and tissues.Magnetic, fluorescence, or dual cell separation.Probes for MRI. Specifications:Iron Oxide Core Diameter: 8 – 10 nmHydrodynamic Diameter: 50 – 110 nmPolydispersity Index (PDI): < 0.3Magnetization: 5 – 30 emu/g (room temperature)Fluorescent Dye:AFDye 488 (AlexaFluor 488 analog, Abs/Em = 490/525, Filter set: FITC)AFDye 555 (AlexaFluor 555 analog, Abs/Em = 555/580, Filter set: TRITC)AFDye 647 (AlexaFluor 647 analog, Abs/Em = 650/665, Filter set: Cy5)IR750 (IRDye 750 analog, Abs/Em = 756/776, Filter set: Cy7)Shelf life: > 1 year (4°C storage) |