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PF-3450074

PF-3450074

Item no.	TMO-T16500-5mg
Manufacturer	TargetMol
CASRN	1352879-65-2
Amount	5mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	O=C(N[C@@H](CC1=CC=CC=C1)C(N(C)C2=CC=CC=C2)=O)CC3=C(C)NC4=C3C=CC=C4
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	HIV Protease,HIV Protease, PF-74
Available
Short Description	PF-3450074 acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation specific factor 6) and NUP153 (nucleoporin 153), and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle. PF-3450074 is a specifical inhibitor of HIV-1 capsid protein (CA) and shows a broad-spectrum inhibition of HIV isolates with submicromolar potency (EC50=8-640 nM).
Shipping	cool pack
Storage	-20°
Target names or alias	PF-74
Molecular Weight	425, 52
Pathway	Proteases/Proteasome\|\|\|Microbiology/Virology
Target	HIV Protease

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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Delivery expected until 9/27/2024

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