Comparison

N-Boc-4-hydroxy-L-proline methyl ester European Partner

Item no. HY-Y0755-100mg
Manufacturer MedChem Express
CASRN 102195-79-9
Amount 100 mg
Quantity options 100 g 100 mg 1ea 1 g 250 mg 25 g 500 mg
Category
Type Chemicals
Specific against other
Purity 98.06
Citations [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.<br/>[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
Smiles O=C(N1[C@H](C(OC)=O)C[C@H](O)C1)OC(C)(C)C
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Available
Product Description
N-Boc-cis-4-hydroxy-L-proline methyl ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline methyl ester is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
Cancer-programmed cell death
MolecularWeight
245.27
Clinical Information
No Development Reported
Manufacturers Research Area
Cancer
Solubility
10 mM in DMSO
Target
ADC Linker; PROTAC Linkers
Manufacturers Target
ADC Linker; PROTAC Linkers
Isoform
Non-cleavable Linker
Manufacturers Pathway
Antibody-drug Conjugate/ADC Related; PROTAC
Manufacturers Product type
ADC Related

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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