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Sibiromycin

Sibiromycin

Item no.	HY-N9460-10mg
Manufacturer	MedChem Express
CASRN	12684-33-2
Amount	10mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C24H33N3O7
Citations	[1]Gerratana B. Biosynthesis, synthesis, and biological activities of pyrrolobenzodiazepines. Med Res Rev. 2012;32(2):254-293.<br>[2]Li W, et al. Biosynthesis of sibiromycin, a potent antitumor antibiotic. Appl Environ Microbiol. 2009;75(9):2869-2878.
Smiles	O=C1C2=CC(O[C@H]3[C@@H]([C@](O)([C@H]([C@@H](O3)C)NC)C)O)=C(C)C(O)=C2N[C@@H]([C@@]4([H])N1C=C(C4)/C=C/C)O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	Sibiromycin is a naturally produced glycosylated pyrrolobenzodiazepines (PBDs). Sibiromycin is also a potent antitumor antibiotic that binds covalently to DNA in the minor groove at the NH2 of guanine[1][2].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	475.53
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	10 mM in DMSO
Manufacturers Target	Antibiotic; DNA Alkylator/Crosslinker
Pathway	Anti-infection; Cell Cycle/DNA Damage
Manufacturers Product type	Natural Products

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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