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6-Benzoylheteratisine

6-Benzoylheteratisine

Item no.	HY-N9404-5mg
Manufacturer	MedChem Express
CASRN	99759-48-5
Amount	5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.66
Citations	[1]Ameri A. Effects of the alkaloids 6-benzoylheteratisine and heteratisine on neuronal activity in rat hippocampal slices. Neuropharmacology. 1997 Aug;36(8):1039-46.<br>[2]Gutser UT, et al. The alkaloid 6-benzoylheteratisine inhibits voltage-gated Na+ channels in rat brain synaptosomes. Neuropharmacology. 1998 Sep;37(9):1139-46.
Smiles	CO[C@@H]1[C@]23[C@]4([H])[C@@H]([C@@]([C@@]5([C@]6([H])[C@@]3([H])C[C@H](CC5)OC6=O)O)([H])[C@@]2([H])N(C[C@@]4(CC1)C)CC)OC(C7=CC=CC=C7)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	6-Benzoylheteratisine is an Aconitum alkaloid with potential neuroprotective activity. 6-Benzoylheteratisine can antagonize tetrodotoxin, inhibit the increase of [Na+]i, [Ca2+]i and glutamate release, and block sodium channels. 6-Benzoylheteratisine has an inhibitory effect on the neuronal activity underlying epileptiform burst discharge[1][2].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	495.61
Clinical_Information	No Development Reported
Manufacturers Research_Area	Neurological Disease
Solubility	10 mM in DMSO
Manufacturers Target	Sodium Channel
Pathway	Membrane Transporter/Ion Channel
Manufacturers Product type	Natural Products

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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