Comparison

Propiconazole-d3 (nitrate) European Partner

Item no. HY-B0847S1-1mg
Manufacturer MedChem Express
CASRN 2699607-26-4
Amount 1mg
Category
Type Chemicals
Specific against other
Formula C15H15D3Cl2N4O5
Citations [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
Smiles ClC1=CC(Cl)=C(C2(OC([2H])(C([2H])(O2)CCC)[2H])CN3C=NC=N3)C=C1.O=[N+]([O-])O
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Available
Product Description
Propiconazole-d3 (nitrate) is the deuterium labeled Propiconazole nitrate. Propiconazole is a broad-spectrum triazole fungicide that inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption. Propiconazole inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s=0.04 and >200 µM, respectively). Propiconazole inhibits the growth of T. deformans and R. stolonifer (ED50s=0.073 and 4.6 µg/mL, respectively). Propiconazole increases production of reactive oxygen species (ROS).
Shipping
Room temperature
MolecularWeight
408.25
Clinical_Information
No Development Reported
Manufacturers Research_Area
Infection
Solubility
10 mM in DMSO
Manufacturers Target
Fungal; Isotope-Labeled Compounds; Reactive Oxygen Species
Pathway
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Manufacturers Product type
Isotope-Labeled Compounds

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mg
Available: In stock
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