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Nafcillin

Nafcillin

Item no.	HY-B0555-1ea
Manufacturer	MedChem Express
CASRN	147-52-4
Amount	1 ea
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C21H22N2O5S
Citations	[1]Tan, A.K., et al. Identification of the site of covalent attachment of nafcillin, a reversible suicide inhibitor of beta-lactamase. Biochem J, 1992. 281 ( Pt 1): p. 191-6.<br>[2]Palmer, D.L., et al. Bacterial wound colonization after broad-spectrum versus narrow-spectrum antibiotics. Ann Thorac Surg, 1995. 59(3): p. 626-31.<br>[3]Lawrence I. Mortin, et al. Rapid Bactericidal Activity of Daptomycin against Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Peritonitis in Mice as Measured with Bioluminescent Bacteria. Antimicrob Agents Chemother. 2007 May; 51(5): 1787-1794.<br>[4]Sakoulas G, et al. Nafcillin enhances innate immune-mediated killing of methicillin-resistant Staphylococcus aureus. J Mol Med (Berl). 2014 Feb;92(2):139-49.
Smiles	OC([C@@H]1N(C2=O)[C@]([C@@H]2NC(C(C3=CC=CC=C3C=C4)=C4OCC)=O)([H])SC1(C)C)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	Nafcillin, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin exhibits bactericidal activity, and can be used for the research of staphylococcal infections[1][2][3][4].
Shipping	Room temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	414.47
Clinical_Information	Launched
Manufacturers Research_Area	Infection
Solubility	10 mM in DMSO
Manufacturers Target	Antibiotic; Bacterial; Beta-lactamase
Isoform	β-lactam
Pathway	Anti-infection
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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