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Alpha-Estradiol-d2

Alpha-Estradiol-d2

Item no.	HY-B0141AS1-1mg
Manufacturer	MedChem Express
CASRN	81586-94-9
Amount	1 mg
Quantity options	1 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.0
Formula	C18H22D2O2
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.<br/>[2]Santos RS, et al. The effects of 17 alpha-estradiol to inhibit inflammation in vitro. Biol Sex Differ. 2017 Sep 6;8:30.<br/>[3]Schriefers H, et al. Inhibition of testosterone metabolism by 17-alpha-estradiol in rat liver slices. Arzneimittelforschung. 1991 Nov;41(11):1186-9.<br/>[4]Zhang HB, et al. 17-Alpha-estradiol ameliorating oxygen-induced retinopathy in a murine model. Jpn J Ophthalmol. 2012 Jul;56(4):407-15.
Smiles	C[C@@]12[C@H](O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=C([2H])C(O)=C4[2H])[C@@]3([H])CC2
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	Alfatradiol-d2; Epiestradiol-d2; Epiestrol-d2
Available
Product Description	Alpha-Estradiol-d2 is the deuterium labeled Alpha-Estradiol. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	274.39
Clinical Information	No Development Reported
Manufacturers Research Area	Metabolic Disease; Cardiovascular Disease
Solubility	10 mM in DMSO
Target	5 alpha Reductase; Endogenous Metabolite
Manufacturers Target	5 alpha Reductase; Endogenous Metabolite
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Isotope-Labeled Compounds

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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