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Degarelix-d7

Degarelix-d7

Item no.	HY-16168AS-5mg
Manufacturer	MedChem Express
Amount	5mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C82H96D7ClN18O16
Citations	[1]Rick FG, et al. An update on the use of degarelix in the treatment of advanced hormone-dependent prostate cancer. Onco Targets Ther. 2013 Apr 16;6:391-402.<br>[2]Sakai M, et al. In search of the molecular mechanisms mediating the inhibitory effect of the GnRH antagonistdegarelix on human prostate cell growth. PLoS One. 2015 Mar 26;10(3):e0120670.<br>[3]Sonesson A, et al. Metabolite profiles of degarelix, a new gonadotropin-releasing hormone receptor antagonist, in rat, dog, and monkey. Drug Metab Dispos. 2011 Oct;39(10):1895-903.<br>[4]Broqua P, et al. Pharmacological profile of a new, potent, and long-acting gonadotropin-releasing hormoneantagonist: degarelix. J Pharmacol Exp Ther. 2002 Apr;301(1):95-102.<br>[5]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
Smiles	NC(NC(C=C1)=CC=C1C[C@@H](NC([C@@H](NC([C@H](CO)NC([C@H](NC([C@H](NC([C@H](NC(C)=O)CC2=CC3=C(C=CC=C3)C=C2)=O)CC4=CC=C(C=C4)Cl)=O)CC5=CN=CC=C5)=O)=O)CC6=CC=C(C=C6)NC([C@@H]7CC(NC(N7)=O)=O)=O)=O)C(N[C@@H](CC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C(N[C@@H](CCCCNC(C)C)C(N8[C@@H](CCC8)C(N[C@H](C)C(N)=O)=O)=O)=O)=O)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	Degarelix-d7 is deuterium labeled Degarelix. Degarelix is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist.
Shipping	Room temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
MolecularWeight	1639.30
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer; Endocrinology
Solubility	10 mM in DMSO
Manufacturers Target	GnRH Receptor; Isotope-Labeled Compounds
Pathway	GPCR/G Protein; Others
Manufacturers Product type	Isotope-Labeled Compounds

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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