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ODN 2336

ODN 2336

Item no.	HY-150742-1ea
Manufacturer	MedChem Express
CASRN	332956-64-6
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 1 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	90.74
Citations	[1]urk M, et al. C-Class CpG ODN: sequence requirements and characterization of immunostimulatory activities on mRNA level. Immunobiology. 2004;209(1-2):141-54. <br/>[2]old MC, et al. Purified neonatal plasmacytoid dendritic cells overcome intrinsic maturation defect with TLR agonist stimulation. Pediatr Res. 2006 Jul;60(1):34-7.<br/>[3]Hilbert T, et al. Beta2-adrenoceptor stimulation suppresses TLR9-dependent IFNA1 secretion in human peripheral blood mononuclear cells. PLoS One. 2013 May 28;8(5):e65024.
Smiles	[DNA, d(G-sp-G-sp-G-G-A-C-G-A-C-G-T-C-G-T-G-G-sp-G-sp-G-sp-G-sp-G-sp-G)]
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	ODN 2336 is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 induces the production of IFN-α. ODN 2336 up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 can be used as adjuvant of vaccines[1][2][3].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	6761.70
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology
Solubility	H2O : 20 mg/mL (ultrasonic)
Target	Toll-like Receptor (TLR)
Manufacturers Target	Toll-like Receptor (TLR)
Manufacturers Pathway	Immunology/Inflammation
Manufacturers Product type	Oligonucleotides

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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