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ODN 1585

ODN 1585

Item no.	HY-150725-1ea
Manufacturer	MedChem Express
CASRN	386832-46-8
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 1 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	93.90
Citations	[1]Gramzinski RA, et al. Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice. Infect Immun. 2001 Mar;69(3):1643-9.<br/>[2]Blazar BR, et al. Synthetic unmethylated cytosine-phosphate-guanosine oligodeoxynucleotides are potent stimulators of antileukemia responses in naive and bone marrow transplant recipients. Blood. 2001 Aug 15;98(4):1217-25.<br/>[3]Krug A, et al. Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells. Eur J Immunol. 2001 Jul;31(7):2154-63.
Smiles	[DNA, d(G-sp-G-G-G-T-C-A-A-C-G-T-T-G-A-G-G-sp-G-sp-G-sp-G-sp-G)]
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	ODN 1585 is a potent inducer of IFN and TNFα production. ODN 1585 is a potent stimulator of NK (natural killer) function. ODN 1585 increases CD8+ T-cell function, including the CD8+ T cell-mediated production of IFN-γ. ODN 1585 induces regression of established melanomas in mice. ODN 1585 can confer complete protection against malaria in mice. ODN 1585 can be used for acute myelogenous leukemia (AML) and malaria research. ODN 1585 can be used as a vaccine adjuvant[1][2][3].
StorageTemperature	-20°C (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	6430.00
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer; Infection; Inflammation/Immunology
Solubility	H2O : 20 mg/mL (ultrasonic)
Target	IFNAR; TNF Receptor
Manufacturers Target	IFNAR; TNF Receptor
Isoform	TNFRSF5/CD40
Manufacturers Pathway	Apoptosis; Immunology/Inflammation
Manufacturers Product type	Oligonucleotides

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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