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Zonampanel

Zonampanel

Item no.	HY-15072-50mg
Manufacturer	MedChem Express
CASRN	210245-80-0
Amount	50 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	98.06
Formula	C13H9N5O6
Citations	[1]Minematsu T, et al. Characterization of renal tubular apical efflux of zonampanel, an alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, in humans. Xenobiotica. 2008 Sep;38(9):1191-202.<br>[2]Minematsu T, et al. Role of organic anion transporters in the pharmacokinetics of zonampanel, an alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, in rats. Drug Metab Dispos. 2008 Aug;36(8):1496-504.
Smiles	O=C(N1CC(O)=O)C(NC(C1=C2)=CC([N+]([O-])=O)=C2N3C=CN=C3)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	YM 872
Available
Product Description	Zonampanel (YM 872) is a selective antagonist of the glutamate receptor subtype, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor.
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
MolecularWeight	331.24
Clinical_Information	Phase 2
Manufacturers Research_Area	Metabolic Disease
Solubility	DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	iGluR
Isoform	AMPA Receptor
Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Reference compound

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