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TSPO ligand-2

TSPO ligand-2

Item no.	HY-150409-10mg
Manufacturer	MedChem Express
CASRN	1160640-95-8
Amount	10 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.63
Formula	C23H29NO8
Citations	[1]Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.
Smiles	O=C(O[C@H]1[C@@H](OC)[C@@]([C@]2(C)[C@@H](C/C=C(C)\C)O2)([H])[C@]3(OC3)CC1)OC4=CC=C([N+]([O-])=O)C=C4
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	TSPO ligand-2 is a ligand of AUTAC1. AUTAC1 contains an p-fluorobenzylguanine (FBnG) and a Fumagillol moiety, which can silence endogenous MetAP2 in HeLa cells[1].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	447.48
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 50 mg/mL (ultrasonic; warming; heat to 70°C)
Target	AUTACs
Manufacturers Target	AUTACs
Manufacturers Pathway	Autophagy; PROTAC
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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