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MptpB-IN-1

MptpB-IN-1

Item no.	HY-145741-100mg
Manufacturer	MedChem Express
CASRN	2244622-44-2
Amount	100 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Citations	[1]Vickers CF, et al. Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo. J Med Chem. 2018;61(18):8337-8352.
Smiles	O=C(C1=NOC(C)=C1C2=CC=CC(C3=CC(Cl)=C(C(Cl)=C3)O)=C2)O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden[1].
Shipping	Room temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	364.18
Clinical Information	No Development Reported
Manufacturers Research Area	Infection
Solubility	10 mM in DMSO
Target	Antibiotic
Manufacturers Target	Antibiotic
Manufacturers Pathway	Anti-infection
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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