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ERα antagonist 1

ERα antagonist 1

Item no.	HY-144733-1ea
Manufacturer	MedChem Express
CASRN	2762423-09-4
Amount	1 ea
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C33H32N2O5S
Citations	[1]Bai C, et al. Benzothiophene derivatives as selective estrogen receptor covalent antagonists: Design, synthesis and anti-ERα activities. Bioorg Med Chem. 2021 Oct 1;47:116395.
Smiles	O=C(C1=C(SC2=CC(O)=CC=C21)C3=CC=C(C=C3)O)C4=CC=C(C=C4)OC5CN(C5)C/C=C/C(N6CCCCC6)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	ERα antagonist 1 (Compound 19d) is a potent, selective, covalent estrogen receptor α (ERα) antagonist. ERα antagonist 1 induces apoptosis and cell cycle G0/G1 phase arrest in MCF-7 cells[1].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	568.68
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	10 mM in DMSO
Manufacturers Target	Apoptosis; Estrogen Receptor/ERR
Isoform	ERα
Pathway	Apoptosis; Vitamin D Related/Nuclear Receptor
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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