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FPI-1465

FPI-1465

Item no.	HY-139744-1ea
Manufacturer	MedChem Express
CASRN	1452458-70-6
Amount	1 ea
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C11H18N4O7S
Citations	[1]Andrew M King, et al. Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins. ACS Chem Biol. 2016 Apr 15;11(4):864-8.
Smiles	O=C([C@H]1[N@@]2C(N([C@H](CC1)C2)OS(=O)(O)=O)=O)NO[C@@H]3CCNC3
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	FPI-1465 acts a dual inhibitor of serine-β-Lactamases and Penicillin-binding proteins (PBPs).FPI-1465 inhibits PBP2 (IC50=1.0 µg/mL). FPI-1465 exhibits activity against β-lactamase CTX-M-15 and OXA-48 with Kds of 0.011 and 5.3 µM, respectively[1].
Shipping	Room temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	350.35
Clinical_Information	No Development Reported
Manufacturers Research_Area	Infection
Solubility	10 mM in DMSO
Manufacturers Target	Bacterial; Beta-lactamase; Penicillin-binding protein (PBP)
Pathway	Anti-infection
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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