« Back
Home /
(±)11(12)-EET-d11

(±)11(12)-EET-d11

Item no.	HY-130494S-1mg
Manufacturer	MedChem Express
CASRN	2699607-19-5
Amount	1mg
Quantity options	10 ug 1ea 1mg 25 ug 5mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C20H21D11O3
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. <br/>[2] Luo XQ, et al. Epoxyeicosatrienoic acids inhibit the activation of NLRP3 inflammasome in murine macrophages. J Cell Physiol. 2020;235(12):9910-9921.<br/>[3]Chacos N, et al. Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid. Biochem Biophys Res Commun. 1982;104(3):916-922.<br/>[4]Oliw EH, et al. Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates. J Biol Chem. 1982;257(7):3771-3781.<br/>[5]Capdevila JH, et al. Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase. J Lipid Res. 2000;41(2):163-181.<br/>[6]Wang Z, et al. Arachidonic acid inhibits basolateral K channels in the cortical collecting duct via cytochrome P-450 epoxygenase-dependent metabolic pathways. Am J Physiol Renal Physiol. 2008;294(6):F1441-F1447.<br/>[7]Spector AA. Arachidonic acid cytochrome P450 epoxygenase pathway. J Lipid Res. 2009;50 Suppl(Suppl):S52-S56.
Smiles	[2H]C([2H])(C([2H])(/C=C\C[C@@H]1[C@H](C/C=C\C/C=C\CCCC(O)=O)O1)[2H])C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H]
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	(±)11,12-EET-d11
Available
Product Description	(±)11(12)-EET-d11 is the deuterium labeled (±)11(12)-EET. (±)11(12)-EET is a NLRP3 inflammasome inhibitor. (±)11(12)-EET can be used for the research of anti-inflammatory, angiogenic and cardioprotective[1][2][3][4][6].
Shipping	Room temperature
MolecularWeight	331.53
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology; Cardiovascular Disease
Solubility	10 mM in DMSO
Target	NOD-like Receptor (NLR)
Manufacturers Target	NOD-like Receptor (NLR)
Manufacturers Pathway	Immunology/Inflammation
Manufacturers Product type	Isotope-Labeled Compounds

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1mg

available

Request delivery time