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3,5-Diiodothyropropionic acid

3,5-Diiodothyropropionic acid

Item no.	HY-126236-50mg
Manufacturer	MedChem Express
CASRN	1158-10-7
Amount	50 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.20
Citations	[1]Pennock GD, et al. Cardiac effects of 3,5-diiodothyropropionic acid, a thyroid hormone analog with inotropic selectivity. J Pharmacol Exp Ther. 1992 Oct;263(1):163-9.
Smiles	O=C(O)CCC1=CC(I)=C(OC2=CC=C(O)C=C2)C(I)=C1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	3, 5-Diiodothyropropionic acid is a thyroid hormone analog, induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (TR), with Ka of 2.40 and 4.06 M-1 for TRα1 and TRβ1, respectively[1].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	510.06
Clinical_Information	Phase 2
Manufacturers Research_Area	Cardiovascular Disease; Endocrinology
Solubility	DMSO : 50 mg/mL (ultrasonic)
Manufacturers Target	Thyroid Hormone Receptor
Pathway	Vitamin D Related/Nuclear Receptor
Manufacturers Product type	Reference compound

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