USL311

Item no.	HY-114244-100mg
Manufacturer	MedChem Express
CASRN	1373268-67-7
Amount	100 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.97
Formula	C24H34N6O
Citations	[1]Peter Richardson. Usl-311 for use in the treatment of cancer. WO2018162924A1<br>[2]Takacs GP, et al. Modulation of the chemokine/chemokine receptor axis as a novel approach for glioma therapy. Pharmacol Ther. 2021 Jun;222:107790.
Smiles	O=C(C1=NC(N2CCN(C3CCN(C(C)C)CC3)CCC2)=CC=C1)NC4=CC=NC=C4
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	USL311 is a potent and selective CXCR4 antagonist, with anti-tumor activity. USL311 prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	422.57
Clinical_Information	Phase 2
Manufacturers Research_Area	Cancer; Endocrinology
Solubility	DMSO : 18.57 mg/mL (ultrasonic; warming; heat to 80°C)
Manufacturers Target	CXCR
Isoform	CXCR4
Pathway	GPCR/G Protein; Immunology/Inflammation
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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