Comparison

FAAH-IN-6 European Partner

Item no. HY-103461-1ea
Manufacturer MedChem Express
CASRN 1143578-94-2
Amount 1 ea
Quantity options 100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category
Type Chemicals
Specific against other
Purity 99.70
Citations [1]Kono M, et al. Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors. Bioorg Med Chem. 2014 Feb 15;22(4):1468-78.
Smiles O=C(N1CCN(C2=NC=CC(C3=CC=C(F)C(F)=C3)=N2)CC1)NC4=NN=CC=C4
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Available
Product Description
FAAH-IN-6 (compound 21d) is a potent, orally active and cross the blood-brain barrier fatty acid amide hydrolase (FAAH) inhibitor with IC50s of 0.72, 0.28 nM for hFAAH, rFAAH, respectively. FAAH-IN-6 shows dose-dependent analgesic efficacy in animal models of both neuropathic and inflammatory pain[1].
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
Neuroscience-Neuromodulation
MolecularWeight
397.38
Clinical Information
No Development Reported
Manufacturers Research Area
Neurological Disease
Solubility
DMSO : 100 mg/mL (ultrasonic)
Target
FAAH
Manufacturers Target
FAAH
Manufacturers Pathway
Metabolic Enzyme/Protease; Neuronal Signaling
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 ea
Available: In stock
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