« Back
Home /
Mouse Cytokine Array C3

Mouse Cytokine Array C3

Item no.	AAM-CYT-3-8
Manufacturer	Raybiotech
Amount	8 Sample Kit
Quantity options	2 Sample Kit 4 Sample Kit 8 Sample Kit
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Neural Signaling Neural Adhesion Molecules By Cell Type Carcinoma Glioma Hematology Leukemia Lymphoma Cell Biology Cell Movement Cell Adhesion Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Adenocarcinoma Mesothelioma Endocrine Regulation of Lipid Metabolism Senescence Enzymes Fatty Acid Synthesis Arrays By Organ Bladder Cancer Breast Cancer Renal Cancer Antibody Arrays
Type	Array
Specific against	Mouse
Host	Hamster - Armenian
Citations	1. Zhou Q, Desta T, Fenton M, Graves DT, Amar S. Cytokine Profiling of Macrophages Exposed to Porphyromonas gingivalis, Its Lipopolysaccharide, or Its FimA Protein. Infect Immun. 2005,73(2):935–943.<br />2. Orientia tsutsugamushi subverts dendritic cell functions by escaping from autophagy and impairing their migration<br />3. Cyclophilin D Extramitochondrial Signaling Controls Cell Cycle Progression and Chemokine-Directed Cell Motility<br />4. Kang TW., et al. Senescence surveillance of pre-malignant hepatocytes limits liver cancer development. Nature. 2011 Nov 9,479(7374):547-51. doi: 10.1038/nature10599.<br />5. Kang TW., et al. Senescence surveillance of pre-malignant hepatocytes limits liver cancer development. Nature. 2011 Nov 9,479(7374):547-51. doi: 10.1038/nature10599.<br />6. Li, H et al. IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation. IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation. IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation. J. Exp. Med. Volume 201, Issue 7, Pages 1169-77, Apr 2005<br />7. Acres B, Gantzer M, Remy C, Futin N, Accart N, et al. Fusokine Interleuikin-2/Interleukin-18, a Novel Potent Innate and Adaptive Immune Stimulator with Decreased Toxicity. Cancer Res. 2005,65(20):9536–9546.<br />8. Venmar K., Carter K., Hwang D., Dozier A., Fingleton B. IL-4 receptor ILR4alpha regulates metastatic colonization by mammary tumors through multiple signaling pathways. Cancer Research Published OnlineFirst June 19, 2014, doi: 10.1158/0008-5472.CAN-14-0093 <br />9. Ehninger D. Tsc2 Haploinsufficiency Has Limited Effects on Fetal Brain Cytokine Levels during Gestational Immune Activation. Autism Research and Treatment. Volume 2014, Article ID 761279, 7 pages http://dx.doi.org/10.1155/2014/761279<br />10. Price P., et al. Chemokine (C-C motif) receptor 1 (CCR1) is required for efficient recruitment of neutrophils during respiratory infection with Modified Vaccinia virus Ankara J. Virol. published ahead of print 9 July 2014 , doi:10.1128/JVI.01524-14 <br />11. Vilatla M., et al. Recruitment of Circulating Breast Cancer Cells Is Stimulated by Radiotherapy. Cell Available online 10 July 2014. http://dx.doi.org/10.1016/j.celrep.2014.06.011<br />12. Palmi C., et al. Cytoskeletal Regulatory Gene Expression and Migratory Properties of B Cell Progenitors are Affected by the ETV6-RUNX1 Rearrangement Mol Cancer Res molcanres.0056.2014, Published OnlineFirst July 24, 2014, doi: 10.1158/1541-7786.MCR-14-0056-T <br />13. Ha CT, Li X-H, Fu D, Moroni M, Fisher C, et al. (2014) Circulating Interleukin-18 as a Biomarker of Total-Body Radiation Exposure in Mice, Minipigs, and Nonhuman Primates (NHP). PLoS ONE 9(10): e109249. doi:10.1371/journal.pone.0109249<br />14. Llorens-Martin M., et al. Peripherally triggered and GSK-3beta-driven brain inflammation differentially skew adult hippocampal neurogenesis, behavioral pattern separation and microglial activation in response to ibuprofen. Translational Psychiatry (2014) 4, e463, doi:10.1038/tp.2014.92, published online 14 October 2014<br />15. Benabid R., et al. Neutrophil Elastase Modulates Cytokine Expression: CONTRIBUTION TO HOST DEFENSE AGAINST PSEUDOMONAS AERUGINOSA-INDUCED PNEUMONIA. THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 287, NO. 42, pp. 34883–34894, October 12, 2012, DOI 10.1074/jbc.M112.361352
ECLASS 5.1	32161000
ECLASS 6.1	32161000
ECLASS 8.0	32161000
ECLASS 9.0	32161000
ECLASS 10.0.1	32161000
ECLASS 10.1	32161000
ECLASS 11.0	32161000
UNSPSC	41116126
Similar products	IFN-gamma, IGFBP-5, IL-10, IL-1 alpha, IL-1 beta, IL-6, TIMP-1, VCAM-1, SCF, IL-13, IL-4, IL-6, Fractalkine, G-CSF, IL-17, VEGF-A, IL-2, CD40, Axl, RANTES, M-CSF, MIP-1 alpha, GM-CSF, IL-5, IL-9, MCP-1, CXCL16, IL-3, Lymphotactin, MIG, TARC, TECK, SDF-1 alpha, LIX, PF-4, Eotaxin-2, CTACK, IL-12 p70, MIP-2, MCP-5, CD30, Eotaxin-1, P-Selectin, Thrombopoietin, MIP-1 gamma, BLC, MIP-3 alpha, MIP-3 beta, TNF alpha, IGFBP-3, Fas Ligand, L-Selectin, Leptin R, CD30 Ligand, sTNFRI, IL-12 p40/p70, sTNFRII, IGFBP-6, CRG-2, TCA-3, KC/CXCL1, Leptin/OB, IL-3 Rb
Available
Number of Targets Detected	62
Species Detected	Mouse
Compatible Sample Types	Cell Culture Supernatants Cell Lysates Plasma Serum Tissue Lysates
Design Principle	Sandwich-based
Method of Detection	Chemiluminescence
Quantitative/Semi-Quantitative	Semi-Quantitative
Solid Support	Membrane
Gene Symbols	AXL \| CCL1 \| CCL11 \| CCL12 \| CCL17 \| CCL19 \| CCL2 \| CCL20 \| CCL24 \| CCL25\| CCL27 \| CCL3 \| CCL5 \| CCL9 \| CD40 \| CSF1 \| CSF2 \| CSF2RB \| CSF3 \| CX3CL1 \| CXCL1 \| CXCL10 \| CXCL12 \| CXCL13 \| CXCL16 \| CXCL2 \| CXCL5 \| CXCL9 \| FASLG \| IFNG \| IGFBP3 \| IGFBP5 \| IGFBP6 \| IL10 \| IL12A \| IL13 \| IL17A \| IL1A \| IL1B \| IL2 \| IL3 \| IL4 \| IL5 \| IL6 \| IL9 \| KITLG \| LEP \| LEPR \| PF4 \| SELL \| SELP \| THPO \| TIMP1 \| TNF \| TNFRSF8 \| TNFSF8 \| TPO \| VCAM1 \| VEGFA \| XCL1
Application Information	Multiplexed Protein Detection Detection of Relative Protein Expression Detecting Patterns of Cytokine Expression Biomarker/ Key Factor Screening Identifying Key Factors Confirming a Biological Process
Kit Components	Mouse Cytokine Antibody Array C3 Membranes Blocking Buffer Wash Buffer 1 Wash Buffer 2 Biotinylated Detection Antibody Cocktail Streptavidin- Conjugated H R P Detection Buffer C Detection Buffer D Lysis Buffer8- Well Incubation Tray Plastic Sheets Array Templates Manual
Other Materials Required	Pipettors, pipet tips and other common lab consumables Orbital shaker or oscillating rocker Tissue Paper, blotting paper or chromatography paper Adhesive tape or Saran Wrap Distilled or de-ionized water A chemiluminescent blot documentation system (such as U V P's Chemi Doc- It® or Epi Chem I I Benchtop Darkroom or G E's Image Quant™ L A S 4000 or Amersham Imagers 600 and 680), X-ray Film and a suitable film processor, or another chemiluminescent detection system.
Protocol Outline	Block membranes Incubate with Sample Incubate with Biotinylated Detection Antibody Cocktail Incubate with H R P- Conjugated Streptavidin Incubate with Detection Buffers Image with chemiluminescent imaging system Perform densitometry and analysis
Product Features	Easy to use No specialized equipment needed Compatible with nearly any liquid sample Proven technology (many publications) Highly sensitive (pg/ml) Sandwich ELISA specificity Higher density than ELISA, Western blot or bead-based multiplex
Storage/Stability	For best results, store the entire kit frozen at -20°C upon arrival. Stored frozen, the kit will be stable for at least 6 months which is the duration of the product warranty period. Once thawed, store array membranes and 1X Blocking Buffer at -20°C and all other reagents undiluted at 4°C for no more than 3 months.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.