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Human RTK Phosphorylation Array G1

Human RTK Phosphorylation Array G1

Item no.	AAH-PRTK-G1-8
Manufacturer	Raybiotech
Amount	8 Sample Kit
Quantity options	4 Sample Kit 8 Sample Kit
Category	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Neural Adhesion Molecules By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Movement Cell Adhesion Obesity Cell Culture Cytokines Adenocarcinoma Myelofibrosis Endocrine Regulation of Lipid Metabolism Arrays Astrocytoma By Organ Lung Cancer Bladder Cancer Colorectal Cancer Breast Cancer Heart & Blood Cancer Testicular & Prostate Cancer Antibody Arrays
Type	Array
Specific against	Human
Host	Hamster - Armenian
Citations	1. Qi W, Cooke LS, Stejskal A, Riley C, Croce KD, et al. MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer. BMC Cancer. 2009,9:142. doi:10.1186/1471-2407-9-142
ECLASS 10.1	32161000
ECLASS 11.0	32161000
UNSPSC	41116126
Similar products	EphA2, EphB2, FGFR2, RYK, TYRO10, RET, SYK, EGFR, FGFR1, VEGFR2, ZAP70, JAK1, LCK, MUSK, FAK, ALK, Axl, Csk, Fgr, FRK, Fyn, Hck, Itk, Lyn, MATK, ROR1, Tec, Tyk2, ROR2, JAK2, JAK3, LTK, TNK1, ABL1, SCFR, VEGFR3, ACK1, Tie-1, ROS, BMX, FER, SRMS, TXK, Blk, ErbB3, ErbB2, TRKB, EphA7, EphA8, EphB1, EphB6, IGF-1 R, Tie-2, Btk, PYK2, Dtk, EphB4, ErbB4, EphA6, EphB3, M-CSF R, EphA5, EphA4, EphA3, EphA1, Insulin R, NGF R, HGF R, FGFR2 (alpha isoform), PDGF R-alpha, PDGF R-beta
Available
Number of Targets Detected	71
Species Detected	Human
Compatible Sample Types	Cell Culture Supernatants Cell Lysates Plasma Serum Tissue Lysates
Design Principle	Sandwich-based
Method of Detection	Fluorescence Laser Scanner
Quantitative/Semi-Quantitative	Semi-Quantitative
Solid Support	Glass Slide
Gene Symbols	ABL1 \| AXL \| BLK \| BMX \| BTK \| CSF1R \| CSK \| DDR2 \| EGFR \| EPHA1\| EPHA2 \| EPHA3 \| EPHA4 \| EPHA5 \| EPHA6 \| EPHA7 \| EPHA8 \| EPHB1 \| EPHB2 \| EPHB3 \| EPHB4 \| EPHB6 \| ERBB2 \| ERBB3 \| ERBB4 \| FER \| FGFR1 \| FGFR2 \| FGR \| FLT4 \| FRK \| FYN \| HCK \| IGF1R \| INSR \| ITK \| JAK1 \| JAK2 \| JAK3 \| KDR \| KIT \| LCK \| LTK \| LYN \| MATK \| MET \| MUSK \| NGFR \| NTRK2 \| PDGFRA \| PDGFRB \| PTK2 \| PTK2B \| RET \| ROR1 \| ROR2 \| ROS1 \| RYK \| SLPI \| SRMS \| SYK \| TEC \| TEK \| TIE1 \| TNK1 \| TNK2 \| TXK \| TYK2 \| TYRO3 \| ZAP70
Application Information	Multiplexed Protein Detection Detection of Relative Protein Expression Detecting Patterns of Cytokine Expression Biomarker Screening Identifying Key Factors Confirming a Biological Process
Kit Components	Human R T K Phosphorylation Antibody Array G1 Slide(s) Blocking Buffer Wash Buffer 1 Wash Buffer 2 Biotinylated Detection Antibody Cocktail Streptavidin- Conjugated Fluor Lysis Buffer Protease Inhibitor Cocktail Phosphatase Inhibitor Cocktail I I Adhesive Plastic Strips30 ml Centrifuge Tube Manual
Other Materials Required	Small plastic boxes or containers Pipettors, pipette tips and other common lab consumables Orbital shaker or oscillating rocker Aluminum foil Gene microarray scanner or similar laser fluorescence scanner
Protocol Outline	Dry the glass slide Block array surface Incubate with Sample Incubate with Biotinylated Detection Antibody Cocktail Incubate with Streptavidin- Conjugated Fluor Disassemble the glass slide Scan with a gene microarray laser scanner Perform densitometry and analysis
Product Features	High sensitivity and specificity Low sample volume (10-100 µl per array) Large dynamic range of detection Compatible with most sample types Test 4 or 8 samples on each slide Suitable for high-throughput assays
Pathway	PI3K-AKT Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

AAH-PRTK-G1-8.pdf

AAH-PRTK-G1-8-datasheet.pdf

AAH-PRTK-G1-8-safety-datasheet.pdf