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Rabbit Anti-Human BIM

Rabbit Anti-Human BIM

Item no.	RB-02-0035-200
Manufacturer	Raybiotech
Amount	200 ug
Category	Oncology Antibodies ELISA Primary Antibodies By Organ Colorectal Cancer Heart & Blood Cancer Testicular & Prostate Cancer
Type	Antibody
Format	Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1x PBS to a final concentration of 1 mg/ml.
Applications	ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Bim
Available
Target Name	Bim
Accession Number	O43521
Gene Symbol	BCL2L11
Gene ID	10018
Target Synonyms	BOD, BimL, BimEL, BimS, BIM
Conjugate/Tag/Label	Biotin
Application notes:	ELISA (recommended work dilution= 1:2, 000-5, 000), Western Blotting( recommended work dilution= 5 ug/ml), Immunoprecipitation, Blocking peptide with pThr231 (20 uL (mg/ml))(recommended work dilution= (mg/ml) Determined by customer)
Product Description	Bim/Bod is a pro-apoptotic protein belonging to the BH3-only group of Bcl-2 family members, including Bad, Bid, Bik, Hrk and Noxa, which contain a BH3 domain but lack other conserved BH1 or BH2 domains. Bim induces apoptosis by binding to and antagonizing anti-apoptotic members of the Bcl-2 family. Interactions have been observed with Bcl-2, Bcl-xL, Mcl-1, Bcl-w, Bfl-1 and BHRF-1. Bim functions in regulating apoptosis associated with thymocyte negative selection and following growth factor withdrawal, during which Bim expression is elevated. Three major isoforms of Bim are generated by alternative splicing: BimEL, BimL and BimS.
Immunogen	Immunogen was a synthetic peptide derived from human Tau. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells derived from the immunized mouse. The IgM fraction of cell culture supernatant was purified by affinity chromatography.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.