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Rabbit Anti-Human SMAC

Rabbit Anti-Human SMAC

Item no.	RB-02-0029-100
Manufacturer	Raybiotech
Amount	100 ug
Category	Oncology Antibodies ELISA Primary Antibodies By Organ Breast Cancer
Type	Antibody
Format	Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1 x PBS to a final concentration of 1 mg/ml.
Applications	ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	SMAC
Available
Target Name	SMAC
Accession Number	Q9NR28
Gene Symbol	DIABLO
Gene ID	56616
Target Synonyms	SMAC, DIABLO-S, FLJ25049, FLJ10537, DFNA64, second mitochondria-derived activator of caspase
Conjugate/Tag/Label	Biotin
Application notes:	ELISA (recommended work dilution= 1: 64, 000), Western Blotting (recommended work dilution= 1: 1, 000)
Product Description	Second mitochondria-derived activator of caspases, SMAC is a mitochondrial protein that promotes cytochrome-c dependent activation by eliminating the inhibition via IAP - a protein that negatively regulates apoptosis or programmed cell death. Smac is normally a mitochondrial protein but is found in the cytosol when a cell is primed for apoptosis by the final execution step of caspase activation. Smac is the second protein in the apoptosis link, along with cytochrome c, that promotes apoptosis by activating caspases. SMAC is an inhibitor of apoptosis protein (IAP)-binding protein. This mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs.
Immunogen	The immunogen was a synthetic peptide (SMAC). This antibody was produced from a rabbit immunized with this peptide conjugated with KLH. The IgG fraction was purified from rabbit serum by Protein G affinity chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.