Anti-ACE2 (N-term) Antibody

Antibodies|Primary Antibodies

12 months from the date of shipment when stored properly.

Phosphate buffered saline

IgG concentration 1.0 mg/ml (lot specific)

This product is specific for human Angiotensin-converting enzyme 2 (ACE2). ACE2 is a carboxypeptidase which is expressed in a range of tissues including heart, kidney, testis and the gastrointestinal system. ACE2 is a homologue of ACE (Angiotensin-converting enzyme 1), although it has a distinct catalytic activity. ACE2 catalyzes the cleavage of active angiotensin II into angiotensin 1-7, which may counteract the effects of ACE by increasing vasodilatation.A recent discovery is that ACE2 serves as the cellular entry point for the severe acute respiratory syndrome (SARS) virus, functioning as a receptor for the SARS Spike protein.

Synthetic peptide corresponding to a sequence within the amino terminus of human ACE2.