Comparison

Anti-ACAA2 Rabbit pAb

Item no. PTM-6906
Manufacturer PTM Biolabs
Amount 100 ul
Format Lyophilized powder
Applications WB, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
Alias 3-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase, T1
Shipping condition Room temperature
Available
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
ACAA2
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Manufacturer - Research Area
Cardiovascular Biology, Signal Transduction, Metabolism
Product description
In the production of energy from fats, acetyl-Coenzyme A acyltransferase 2 (ACAA2) is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free CoA, ACAA2 catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. ACAA2 also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. ACAA2 also displays hydrolase activity on various fatty acyl-CoAs. Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation.
Purification Method
Protein A and immunogen affinity purified
Constituents
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Polyclonal
Stability
Stable for 12 months from date of receipt/reconstitution.
Background
In the production of energy from fats, acetyl-Coenzyme A acyltransferase 2 (ACAA2) is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free CoA, ACAA2 catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. ACAA2 also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. ACAA2 also displays hydrolase activity on various fatty acyl-CoAs. Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation.
Cellular Localization
Mitochondrion

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
available

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