Item no. |
PTM-6816 |
Manufacturer |
PTM Biolabs
|
Amount |
100 ul |
Format |
Lyophilized powder |
Applications |
WB |
Clone |
JMMR-3565 |
Specific against |
Human (Homo sapiens), Monkey (Cynomolgus, Simian) |
Host |
Rabbit |
Isotype |
IgG Kappa |
Conjugate/Tag |
Unconjugated |
Alias |
ESRRA, ERR1, ESRL1, NR3B1 |
Shipping condition |
Room temperature |
Available |
|
Manufacturer - Type |
Primary Antibodies |
Manufacturer - Category |
Uncategorized |
Manufacturer - Targets |
Estrogen Related Receptor alpha |
Shipping Temperature |
Ambient temperature |
Storage Conditions |
Store at -20°C. Avoid freeze/thaw cycles. |
Manufacturer - Research Area |
Epigenetics , Signal Transduction, Cancer, Metabolism, Neuroscience |
Product description |
The estrogen-related receptor (ERR) subfamily of orphan nuclear receptors include three protein receptors, ERRα/NR3B1, ERRβ/NR3B2, and ERRγ/NR3B3, that have yet to be associated with natural ligands. PGC-1 coactivators regulate ERR transcription activation ability and receptor-induced transcription of genes involved in lipid metabolism, glucose metabolism, and mitochondrial biogenesis. |
Purification Method |
Protein A purified |
Constituents |
PBS, Glycerol, BSA |
PTM |
Unmodified |
Clonality |
Recombinant Monoclonal |
Stability |
Stable for 12 months from date of receipt/reconstitution. |
Background |
The estrogen-related receptor (ERR) subfamily of orphan nuclear receptors include three protein receptors, ERRα/NR3B1, ERRβ/NR3B2, and ERRγ/NR3B3, that have yet to be associated with natural ligands. PGC-1 coactivators regulate ERR transcription activation ability and receptor-induced transcription of genes involved in lipid metabolism, glucose metabolism, and mitochondrial biogenesis. |
Cellular Localization |
Nucleus, Cytoplasm |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.