Anti-Rab5A Mouse mAb

Primary Antibodies

Rab5A

Store at -20°C. Avoid freeze/thaw cycles.

RAB5A is a member of the Ras superfamily of small Rab GTPases. RAB5A is localized at the plasma membrane and early endosomes and functions as a key regulator of vesicular trafficking during early endocytosis. The conformational change between Rab5 GTP/GDP states is essential for its biological function as a rate limiting regulator at multiple steps during endocytosis. RAB5A exerts its function by interacting with several Rab5-specific effectors. These proteins form complexes with Rab5 on a specialized Rab domain of the endosome and promote recycling of RAB5A-cargo targets between endosome and the plasma membrane.

PBS, Glycerol, BSA

Recombinant Monoclonal

RAB5A is a member of the Ras superfamily of small Rab GTPases. RAB5A is localized at the plasma membrane and early endosomes and functions as a key regulator of vesicular trafficking during early endocytosis. The conformational change between Rab5 GTP/GDP states is essential for its biological function as a rate limiting regulator at multiple steps during endocytosis. RAB5A exerts its function by interacting with several Rab5-specific effectors. These proteins form complexes with Rab5 on a specialized Rab domain of the endosome and promote recycling of RAB5A-cargo targets between endosome and the plasma membrane.