Anti-CD57 Mouse mAb

Primary Antibodies

CD57

Store at -20°C. Avoid freeze/thaw cycles.

CD57, also known as HNK-1 and Leu7, is a terminally sulfated glycan carbohydrate epitope (glyco-epitope) expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans at the cell surface. CD57 is synthesized by the enzyme B3GAT1 and is present on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, as well as neural cells and striated muscle. Studies have shown that CD57 is not expressed on platelets, monocytes, granulocytes, or red blood cells. The CD57 epitope may play a role in neural cell adhesion, and characterizes unique maturation states in T and NK cells. CD57 is an important marker when studying functional immune deficiency in patients with autoimmune diseases, infectious diseases, and cancers.

PBS, Glycerol, BSA

Recombinant Monoclonal

CD57, also known as HNK-1 and Leu7, is a terminally sulfated glycan carbohydrate epitope (glyco-epitope) expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans at the cell surface. CD57 is synthesized by the enzyme B3GAT1 and is present on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, as well as neural cells and striated muscle. Studies have shown that CD57 is not expressed on platelets, monocytes, granulocytes, or red blood cells. The CD57 epitope may play a role in neural cell adhesion, and characterizes unique maturation states in T and NK cells. CD57 is an important marker when studying functional immune deficiency in patients with autoimmune diseases, infectious diseases, and cancers.