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Human STEAP1 Full Length Protein, His Tag (HEK293) European Partner

Item no. ST1-H52H3-20ug
Manufacturer ACROBiosystems
Amount 20 ug
Category
Type Proteins Recombinant
Format Liquid
Specific against Human
Host HEK293
Conjugate/Tag His
Purity >90% as determined by SDS-PAGE.
Dry ice Yes
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias STEAP1, PRSS24, STEAP
Available
Buffer
50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 41.7 kDa. The protein migrates as 31 kDa and 35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Description
Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III). Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.
Endotoxin Level
Less than 1.0 EU per ug by the LAL method.
Exp Region
Gln 2 - Leu 339
Expression System
HEK293
Molecular Weight
41.7 kDa
Molecule
STEAP1
SDS-PAGE Legend
Human STEAP1 Full Length, His Tag (HEK293) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Storage
-70C
Host Information
Human STEAP1 Full Length, His Tag (HEK293) (ST1-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 2 - Leu 339 (Accession # Q9UHE8-1).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
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