« Back
Home /
SARS-CoV-2 Spike RBD Protein, His Tag (BA.2.12.1/Omicron) (MALS verified)

SARS-CoV-2 Spike RBD Protein, His Tag (BA.2.12.1/Omicron) (MALS verified)

Manufacturer	ACROBiosystems
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	SARS-CoV-2
Format	Powder
Amount	100 ug
Host	HEK293
Item no.	SPD-C522q-100ug
Conjugate/Tag	Unconjugated, HIS
eClass 6.1	34160400
eClass 9.0	42020190
Available
Alias	Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD
Purity	95%
Manufacturers Category	Protein / Viral Proteins
Description	SARS-CoV-2 Spike RBD, His Tag (BA.2.12.1/Omicron) (SPD-C522q) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2.12.1; GISAID clade: GRA).
Molecule	Spike RBD
Exp Region	Arg 319 - Lys 537
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	26.7 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.7 kDa. The protein migrates as 34-37 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ug

available

Delivery expected until 7/26/2024

Express Delivery: Save 3 days

Compare

Add to wishlist

Recommend by mail