« Back
Home /
Mouse Siglec-2 / CD22 Protein, His Tag

Mouse Siglec-2 / CD22 Protein, His Tag

Manufacturer	ACROBiosystems
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Mouse
Format	Powder
Amount	100 ug
Host	HEK293
Item no.	SI2-M52Ha-100ug
Conjugate/Tag	Unconjugated, HIS
eClass 6.1	34160400
eClass 9.0	42020190
Available
Alias	CD22,SIGLEC2,BL-CAM,SIGLEC-2,Siglec2,SIGLEC2FLJ22814
Purity	95%
Manufacturers Category	Protein / Bio-Markers & CD Antigens
Description	Mouse Siglec-2, His Tag (SI2-M52Ha) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Arg 702 (Accession # P35329-1).
Molecule	Siglec-2
Exp Region	Ser 22 - Arg 702
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	78.3 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 78.3 kDa. The protein migrates as 100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ug

available

Delivery expected until 7/26/2024

Express Delivery: Save 3 days

Compare

Add to wishlist

Recommend by mail