« Back
Home /
Biotinylated Human Siglec-15 / CD33L3 Protein, His,Avitag™ (recommended for biopanning)

Biotinylated Human Siglec-15 / CD33L3 Protein, His,Avitag™ (recommended for biopanning)

Item no.	SG5-H82E9-200ug
Manufacturer	ACROBiosystems
Amount	200 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Powder
Specific against	Human
Host	HEK293
Conjugate/Tag	Biotin, HIS, Avi
Purity	90%
Citations	(1) Angata T, et al. 2007. Glycobiology. 178(8):838-846. (2) Yusuke K, et al. 2015. Bone. 17:217-226. (3) Hiruma Y. et al. 2011. Biochem Biophys Res Commun. 409(3):424-9.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD33 antigen-like 3,SIGLEC-15,CD33L3,sialic acid-binding Ig-like lectin 15,Siglec15,Siglec-15
Available
Manufacturers Category	Protein / MABSol® Biotin Labeled Proteins
Description	Biotinylated Human Siglec-15 Protein, His, Avitag (SG5-H82E9) is expressed from human 293 cells (HEK293). It contains AA Phe 20 - Thr 263 (Accession # Q6ZMC9-1).
Molecule	Siglec-15
Exp Region	Phe 20 - Thr 263
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	30.1 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 30.1 kDa. The protein migrates as 33-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	25 mM MES, 150 mM NaCl, pH5.5
Background	Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 200 ug

available

Delivery expected until 9/6/2024

Express Delivery: Save 3 days

Compare

Add to wishlist

Recommend by mail