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SARS-CoV-2 S1 protein NTD (A262S), His Tag (MALS verified)

SARS-CoV-2 S1 protein NTD (A262S), His Tag (MALS verified)

Item no.	S1D-C52H5-1mg
Manufacturer	ACROBiosystems
Amount	1 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Powder
Specific against	SARS-CoV-2
Host	HEK293
Conjugate/Tag	Unconjugated, HIS
Purity	90%
Citations	(1) Wan Y, et al. J Virol. 2020. pii: JVI.00127-20. (2) Benvenuto D, et al. J Med Virol. 2020. (3) Chang CY, et al. AMB Express. 2020. 10(1):20.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	S1 protein NTD,Spike protein S1 NTD,BetaCoV S1-NTD,COVID-19
Available
Manufacturers Category	Protein / Viral Proteins
Description	SARS-CoV-2 S1 protein NTD (A262S), His Tag (S1D-C52H5) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1 (A262S)).
Molecule	Spike NTD
Exp Region	Ser 13 - Leu 303
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	34.9 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.9 kDa. The protein migrates as 45-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 9/20/2024

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