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Human S100A14 Protein, His Tag

Human S100A14 Protein, His Tag

Item no.	S14-H5121-1mg
Manufacturer	ACROBiosystems
Amount	1 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Powder
Specific against	Human
Host	E.coli
Conjugate/Tag	Unconjugated, HIS
Purity	95%
Citations	(1) Jin Q., et al., 2011, PLoS ONE 6:E19375-E19375. (2) Chen H., et al., 2012, J. Biol. Chem. 287:17109-17119. (3) Sapkota D., et al., 2012, Oral Oncol. 48:219-225.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	S100A14,S114,S100A15
Available
Manufacturers Category	Protein / Other Recombinant Proteins
Description	Human S100A14, His Tag (S14-H5121) is expressed from E. coli cells. It contains AA Met 1 - His 104 (Accession # Q9HCY8-1).
Molecule	S100A14
Exp Region	Met 1 - His 104
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	12.5 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.5 kDa. The protein migrates as 13 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 150 mM NaCl, pH8.0
Background	Protein S100-A14 (S100A14) is also known as S100 calcium-binding protein A14 (S114), which belongs to the S-100 family, containing one EF-hand domain.S100A14 is a homodimer can interact with AGER. S100A14 can modulate P53/TP53 protein levels, and play a role in the regulation of cell survival and apoptosis at different concentrations via receptor for advanced glycation end products (RAGE).S100A14 also plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

available

Delivery expected until 8/23/2024