FGF-21

Item no.	RLT-M10-047
Manufacturer	ReliaTech
Amount	25ug
Category	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Neural Signaling By Cell Type Carcinoma Hematology Myeloma Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines
Type	Proteins Recombinant
Specific against	Mouse
Host	E.coli
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Synonyms	Fibroblast Growth Factor-21, FGFL
Detection range	Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells.
Description	FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of beta-Klotho as a protein cofactor, signals through the FGFR 1c and 4 receptors, and stimulates insulin-independent glucose uptake by adipocytes. Recombinant Murine FGF-21 is a 20.1 kDa protein containing 182 amino acid residues.
Formulation	lyophilized
Length (aa)	182
Protein Sequence	MAYPIPDSSP LLQFGGQVRQ RYLYTDDDQD TEAHLEIRED GTVVGAAHRS PESLLELKAL KPGVIQILGV KASRFLCQQP DGALYGSPHF DPEACSFREL LLEDGYNVYQ SEAHGLPLRL PQKDSPNQDA TSWGPVRFLP MPGLLHEPQD QAGFLPPEPP DVGSSDPLSM VEPLQGRSPS YAS
NCBI GeneID	56636
Accession Number Protein	NP_064397.1?
Accession Numberm RNA	NM_020013.4
Uniprot	Q9JJN1

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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