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Rat PTK7 / CCK4 Protein, Fc Tag

Rat PTK7 / CCK4 Protein, Fc Tag

Manufacturer	ACROBiosystems
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Rat
Format	Powder
Amount	100 ug
Host	HEK293
Item no.	PT7-R5255-100ug
Conjugate/Tag	Unconjugated, Fc
eClass 6.1	34160400
eClass 9.0	42020190
Available
Alias	PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7
Purity	95%
Manufacturers Category	Protein / Enzymes
Description	Rat PTK7, Fc Tag (PT7-R5255) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Gln 695 (Accession # NP_001382670.1).
Molecule	PTK7
Exp Region	Ala 23 - Gln 695
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	100.7 kDa
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 100.7 kDa. The protein migrates as 120-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	0.1 EU per μg
Buffer	50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Background	PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 7/26/2024

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