Item no. |
PRS-96-473-0.2mg |
Manufacturer |
ProSci
|
Amount |
0.2 mg |
Category |
|
Type |
Proteins Recombinant |
Format |
Lyophilized |
Applications |
WB |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
IL21R, CD360, NILR |
Available |
|
Applications |
This recombinant protein can be used for WB. For research use only. |
Applications |
This recombinant protein can be used for WB. For research use only. |
Buffer |
PBS, pH7.4 |
Storage Conditions |
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles. |
Disclaimer |
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures. |
Predicted Molecular Weight |
25.8 kDa |
Purity |
>92% as determined by SDS-PAGE. |
Background |
Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. |
1St Image Caption3 |
The purity of rh IL21R / CD360 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue. |
Background References 1 |
Hamming O.J., et al., 2012, J. Biol. Chem. 287:9454-9460. |
Background References 2 |
Kotlarz D., et al., 2013, J. Exp. Med. 210:433-443. |
Accession # |
AAH04348 |
Ncbi Gene Id # |
50615 |
Ncbi Official Symbol |
IL21R |
Ncbi Official Full Name |
interleukin 21 receptor |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q9HBE5 |
Fusion Tag |
His Tag |
Sequence |
Cys 20 - Pro 236 |
Biological Activity |
Immobilized Biotinylated Human IL-21, Fc Tag at 2ug/mL (100uL/well) can bind Human IL-21 R, His Tag with a linear range of 2-8 ng/mL. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.